Adenovirus 5 E1A Antibody : FITC (OABF01666-FITC)

Product Specifications

Gene Name

Early E1A 32 kDa protein

Gene Aliases

Adenovirus early E1A protein, Control protein E1A, E1A, Early E1A protein, Human adenovirus type 5, Human adenovirus C, pfam02703, E1A_ADE05.

Swiss Prot

P03255

Host

Rabbit

Reactivity

Adenovirus5

Immunogen

KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A

Target

The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC-P, IF

Purification

Purified by Protein A.

Concentration

1 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.