ATG16L1 Antibody (Phospho-Ser287) : HRP (OABF01536-HRP)
Product Specifications
Gene Name
Autophagy related 16-like 1 (S. cerevisiae)
Gene Aliases
IBD10, WDR30, APG16L, ATG16A, ATG16L
Gene ID
55054
Swiss Prot
Q676U5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic phosphopeptide derived from human ATG16A around the phosphorylation site of Ser287
Target
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC-P, IF
Purification
Purified by Protein A.
Concentration
0.6-0.7 mg/mL
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Shipping Conditions
Wet Ice
Fragment
IgG
NCBI Gene Symbol
ATG16L1
Curated Selection
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