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CRKL Antibody (Phospho-Tyr251) : FITC (OABF01311-FITC)

Product Specifications

Gene Name

V-crk avian sarcoma virus CT10 oncogene homolog-like

Gene Aliases

Crk-like protein, CRKL

Gene ID

1399

Swiss Prot

P46109

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Crkl around the phosphorylation site of Tyr251 [CA (p-Y) D]

Target

Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC-P, IF

Purification

Purified by Protein A.

Concentration

1 mg/mL

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Shipping Conditions

Wet Ice

Fragment

IgG

NCBI Gene Symbol

CRKL

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