IRS1 Antibody (Phospho-Ser636/Ser639) : HRP (OABF01191-HRP)
Selected Variant
OABF01191-HRP
Size: 100 µL
Product Specifications
Gene Name
Insulin receptor substrate 1
Gene Aliases
HIRS-1
Gene ID
3667
Swiss Prot
P35568
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser636/639 [PM (p-S) PK (p-S) VS]
Target
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC-P, IF
Purification
Purified by Protein A.
Concentration
0.6-0.7 mg/ml
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Shipping Conditions
Wet Ice
Fragment
IgG
NCBI Gene Symbol
IRS1
NCBI GB Accession Number
IRS1
Host or Source
Rabbit
Price
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