P53-MDM2-IN-7 (hydrochloride)
P53-MDM2-IN-7 (compound 6d) (hydrochloride) is a p53-MDM2 inhibitor. p53-MDM2-IN-7 has an IC50 value of 8.13 μM against A549 cells. p53-MDM2-IN-7 can be used in anti-cancer research[1].
Product Specifications
UNSPSC
12352101
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-mdm2-in-7-hydrochloride.html
Smiles
CC(C)CC1NC2(C(NC3=CC=CC=C32)=O)C(C(C4=CC=C(C5=CC=CC=C5)C=C4)=O)C1C6=CC=C(Br)C=C6.Cl
Molecular Formula
C34H32BrClN2O2
Molecular Weight
615.99
References & Citations
[1]Sivanandhan M, et al. Synthesis, crystal structure, Hirshfeld surface, computational and biological studies of spiro-oxindole derivatives as MDM2-p53 inhibitors. Mol Divers. 2024 Aug 29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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