P53-MDM2-IN-7 (hydrochloride)

P53-MDM2-IN-7 (compound 6d) (hydrochloride) is a p53-MDM2 inhibitor. p53-MDM2-IN-7 has an IC50 value of 8.13 μM against A549 cells. p53-MDM2-IN-7 can be used in anti-cancer research[1].

Product Specifications

UNSPSC

12352101

Target

MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p53-mdm2-in-7-hydrochloride.html

Smiles

CC(C)CC1NC2(C(NC3=CC=CC=C32)=O)C(C(C4=CC=C(C5=CC=CC=C5)C=C4)=O)C1C6=CC=C(Br)C=C6.Cl

Molecular Formula

C34H32BrClN2O2

Molecular Weight

615.99

References & Citations

[1]Sivanandhan M, et al. Synthesis, crystal structure, Hirshfeld surface, computational and biological studies of spiro-oxindole derivatives as MDM2-p53 inhibitors. Mol Divers. 2024 Aug 29.