CLEC5A Antibody: Biotin (OABF01061-Biotin)
Product Specifications
Gene Name
C-type lectin domain family 5, member a
Gene Aliases
Ly10, MDL-, Mdl1, Clecs, Ly100, MDL-1, Clecsf5
Gene ID
23845
Swiss Prot
Q9R007
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from mouse CLEC5A
Target
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, FC, IHC-P, IF
Purification
Purified by Protein A.
Concentration
1 mg/mL
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Shipping Conditions
Wet Ice
Fragment
IgG
NCBI Gene Symbol
CLEC5A
Curated Selection
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