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MAPK8 Antibody (Phospho-Thr183/TYR185) : HRP (OABF00788-HRP)

Selected Variant

OABF00788-HRP

Size: 100 µL

Product Specifications

Gene Name

Mitogen-activated protein kinase 8

Gene Aliases

JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2

Gene ID

5599

Swiss Prot

P45983

Host

Rabbit

Reactivity

Human, Mouse, Rat, Bovine, Dog

Immunogen

KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185

Target

JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC-P, IF

Purification

Purified by Protein A.

Concentration

0.6-0.7 mg/ml

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Shipping Conditions

Wet Ice

Fragment

IgG

NCBI Gene Symbol

MAPK8

NCBI GB Accession Number

MAPK8

Host or Source

Rabbit

Price

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