TJP1 Antibody: HRP (OABF00638-HRP)
Product Specifications
Gene Name
Tight junction protein 1
Gene Aliases
ZO-1
Gene ID
7082
Swiss Prot
Q07157
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig
Immunogen
KLH conjugated synthetic peptide derived from human ZO-1. Immunogen Range: 1670-1720
Target
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC-P, IF, ICC, FC
Purification
Purified by Protein A.
Concentration
0.6-0.7 mg/mL
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Shipping Conditions
Wet Ice
Fragment
IgG
Applications Notes
FCIHC-PIFICC
NCBI Gene Symbol
TJP1
Curated Selection
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