CCR4 Antibody: FITC (OABF00528-FITC)
Product Specifications
Gene Name
Chemokine (C-C motif) receptor 4
Gene Aliases
CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, HGCN:14099
Gene ID
1233
Swiss Prot
P51679
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from human CCR-4
Target
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G (i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC-P, IF
Purification
Purified by Protein A.
Concentration
1 mg/mL
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Shipping Conditions
Wet Ice
Fragment
IgG
NCBI Gene Symbol
CCR4
Curated Selection
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