Melarsomine (dihydrochloride)

Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections[1][2].

Product Specifications

CAS Number

[89141-50-4]

UNSPSC

12352005

Hazard Statement

H301, H319, H332

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/melarsomine-dihydrochloride.html

Purity

95.35

Solubility

10 mM in DMSO

Smiles

NC1=NC(NC(C=C2)=CC=C2[As](SCCN)SCCN)=NC(N)=N1.[H]Cl.[H]Cl

Molecular Formula

C13H23AsCl2N8S2

Molecular Weight

501.33

Precautions

H301, H319, H332

References & Citations

[1]Baneth G, et, al. Dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin. Vet Parasitol. 2002 Apr 30;105 (2) :173-8.|[2]Desquesnes M, et, al. An evaluation of melarsomine hydrochloride efficacy for parasitological cure in experimental infection of dairy cattle with Trypanosoma evansi in Thailand. Parasitology. 2011 Aug;138 (9) :1134-42.