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Ecleralimab

Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP) . Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma[1].

Product Specifications

CAS Number

2415207-91-7

Product Name Alternative

CSJ-117; NVP-CSJ117

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ecleralimab.html

Purity

97.35

Solubility

10 mM in DMSO

Smiles

[Ecleralimab]

Molecular Weight

(46.62 kDa)

References & Citations

[1]Gauvreau GM, et al.Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma. Eur Respir J. 2023 Mar 9;61 (3) :2201193.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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