KDR Antibody - N-terminal region : Biotin (AVARP20010_P050-Biotin)
Selected Variant
AVARP20010_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene Aliases
FLK1, CD309, VEGFR, VEGFR2
Gene ID
3791
Swiss Prot
P35968
Accession Number
NP_002244
Host
Rabbit
Reactivity
Human, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
Target
KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Partner Proteins
FBXO25; VEGFA; MYO1C; CAV1; NPM1; EPN1; SRC; CBL; IQGAP1; UBC; CSNK1D; FBXW11; BTRC; CUL1; AIMP2; SHC2; SYNGAP1; ACP1; ATR; FRS2; SH2D2A; DNM2; NRP1; VEGFC; GRB10; CDH5; GNAQ; SHC1; STAT1; NCK1; SHB; PLCG2; P2RY2; BMX; FIGF; KDR; TIMP3; PTPN6; PTPN11; ITG
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 100%; Horse: 100%; Human: 100%; Pig: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
151kDa
References & Citations
Ohsaka, A., (2008) Biochem. Biophys. Res. Commun. 368 (3), 543-549
Shipping Conditions
Wet Ice
Protein Length
1356
NCBI Gene Symbol
KDR
NCBI GB Accession Number
KDR
Host or Source
Rabbit
Protein Name
Vascular endothelial growth factor receptor 2
Nucleotide Accession Number
NM_002253
Peptide Sequence
LNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSD
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