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TNFSF12 Antibody - N-terminal region: FITC (AVARP20005_P050-FITC)

Product Specifications

Gene Name

Tumor necrosis factor (ligand) superfamily, member 12

Gene Aliases

APO3L, DR3LG, TWEAK, TNLG4A

Gene ID

8742

Swiss Prot

O43508

Accession Number

NP_003800

Host

Rabbit

Reactivity

Human, Mouse, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF12

Target

TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Partner Proteins

DDIT3; TNFSF13B; LYN; OTUB1; TRAF2; BIRC2; AGGF1; TNFRSF12A; TNFRSF25

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Horse: 93%; Human: 100%; Mouse: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Protein Length

249

NCBI Gene Symbol

TNFSF12

Protein Name

Tumor necrosis factor ligand superfamily member 12

Nucleotide Accession Number

NM_003809

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