TNFSF12 Antibody - N-terminal region : FITC (AVARP20005_P050-FITC)
Product Specifications
Gene Name
Tumor necrosis factor (ligand) superfamily, member 12
Gene Aliases
APO3L, DR3LG, TWEAK, TNLG4A
Gene ID
8742
Swiss Prot
O43508
Accession Number
NP_003800
Host
Rabbit
Reactivity
Human, Mouse, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF12
Target
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Partner Proteins
DDIT3; TNFSF13B; LYN; OTUB1; TRAF2; BIRC2; AGGF1; TNFRSF12A; TNFRSF25
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Horse: 93%; Human: 100%; Mouse: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
References & Citations
Jin, L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179
Shipping Conditions
Wet Ice
Protein Length
249
NCBI Gene Symbol
TNFSF12
NCBI GB Accession Number
TNFSF12
Host or Source
Rabbit
Protein Name
Tumor necrosis factor ligand superfamily member 12
Nucleotide Accession Number
NM_003809
Peptide Sequence
QEELVAEEDQDPSELNPQTEESQDPAPFLNRLVRPRRSAPKGRKTRARRA
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