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STXBP1 Antibody - middle region: FITC (AVARP13108_P050-FITC)

Product Specifications

Gene Name

Syntaxin binding protein 1

Gene Aliases

P67, DEE4, NSEC1, UNC18, N-Sec1, RBSEC1, unc-18A, unc18-1, MUNC18-1

Gene ID

6812

Swiss Prot

P61764

Accession Number

NP_001027392

Host

Rabbit

Reactivity

Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human STXBP1

Target

STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.

Partner Proteins

STX19; SYTL4; TRIM38; STX11; STX1A; APBA2; APBA1; UBC; SQSTM1; DYT10; IQCB1; Htt; KCTD3; APP; STX3; STX2; USO1; DOC2B; DOC2A; CDK5R1; PLD2; PLD1; STX1B; PRKCG; PRKCB; PRKCA; NEFM; NEFH; MAPT; CDK5; HGS; Stx5; Dlg4; STX4; TUBB2A; TUBA4A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

Shipping Conditions

Wet Ice

Protein Length

594

NCBI Gene Symbol

STXBP1

Protein Name

Syntaxin-binding protein 1

Nucleotide Accession Number

NM_001032221

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