STXBP1 Antibody - middle region : FITC (AVARP13108_P050-FITC)
Selected Variant
AVARP13108_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Syntaxin binding protein 1
Gene Aliases
P67, DEE4, NSEC1, UNC18, N-Sec1, RBSEC1, unc-18A, unc18-1, MUNC18-1
Gene ID
6812
Swiss Prot
P61764
Accession Number
NP_001027392
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human STXBP1
Target
STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.
Partner Proteins
STX19; SYTL4; TRIM38; STX11; STX1A; APBA2; APBA1; UBC; SQSTM1; DYT10; IQCB1; Htt; KCTD3; APP; STX3; STX2; USO1; DOC2B; DOC2A; CDK5R1; PLD2; PLD1; STX1B; PRKCG; PRKCB; PRKCA; NEFM; NEFH; MAPT; CDK5; HGS; Stx5; Dlg4; STX4; TUBB2A; TUBA4A
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
67kDa
References & Citations
Saitsu, H., (2008) Nat. Genet. 40 (6), 782-788
Shipping Conditions
Wet Ice
Protein Length
594
NCBI Gene Symbol
STXBP1
NCBI GB Accession Number
STXBP1
Host or Source
Rabbit
Protein Name
Syntaxin-binding protein 1
Nucleotide Accession Number
NM_001032221
Peptide Sequence
TRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCA
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