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HMOX2 Antibody - N-terminal region : Biotin (AVARP13071_T100-Biotin)

Selected Variant

AVARP13071_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Heme oxygenase (decycling) 2

Gene Aliases

HO-2

Gene ID

3163

Swiss Prot

P30519

Accession Number

NP_002125

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HMOX2

Target

HEME oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.

Partner Proteins

UBC; MDM2; SKA2; BLOC1S2; ZNF746; ZFP28; ITFG1; JADE1; KIAA1377; NKRF; INPP5K; SNX7; GIT1; SNX5; PLXNB2; IMMT; CEBPZ; HAP1; EIF3C; SHC1; RBBP4; NDUFS2; NR3C1; ATP5B; A2M; USP19; LRIF1; COPS6; KCNMA1; MED31; EEF1G; SETDB1; GPRASP1; CSNK2A1; APP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

HMOX2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Iahikawa, K., et al., (1995) J. Biol. Chem. 270:6345-6350.

Shipping Conditions

Wet Ice

Protein Length

316

NCBI Gene Symbol

HMOX2

NCBI GB Accession Number

HMOX2

Host or Source

Rabbit

Protein Name

Heme oxygenase 2

Nucleotide Accession Number

NM_002134

Peptide Sequence

MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAEN

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