HMOX2 Antibody - N-terminal region : HRP (AVARP13071_P050-HRP)
Selected Variant
AVARP13071_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Heme oxygenase (decycling) 2
Gene Aliases
HO-2
Gene ID
3163
Swiss Prot
P30519
Accession Number
NP_002125
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HMOX2
Target
HEME oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed
Partner Proteins
UBC; MDM2; SKA2; BLOC1S2; ZNF746; ZFP28; ITFG1; JADE1; KIAA1377; NKRF; INPP5K; SNX7; GIT1; SNX5; PLXNB2; IMMT; CEBPZ; HAP1; EIF3C; SHC1; RBBP4; NDUFS2; NR3C1; ATP5B; A2M; USP19; LRIF1; COPS6; KCNMA1; MED31; EEF1G; SETDB1; GPRASP1; CSNK2A1; APP
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Sample Type
HMOX2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
References & Citations
Lovenberg, T.W., et al., (2005) Biochem. Biophys. Res. Commun. 338 (1), 648-652
Shipping Conditions
Wet Ice
Protein Length
316
NCBI Gene Symbol
HMOX2
NCBI GB Accession Number
HMOX2
Host or Source
Rabbit
Protein Name
Heme oxygenase 2
Nucleotide Accession Number
NM_002134
Peptide Sequence
MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAEN
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