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APBA1 Antibody - N-terminal region : Biotin (AVARP13059_P050-Biotin)

Product Specifications

Gene Name

Amyloid beta (A4) precursor protein-binding, family A, member 1

Gene Aliases

X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA

Gene ID

320

Swiss Prot

Q02410

Accession Number

EAW62487

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1

Target

APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Partner Proteins

STXBP1; CNTNAP4; NRXN1; CNTNAP3; KIF17; LIN7B; KCNJ12; CCS; CACNA1B; HTR2C; CASK; NOTCH1; STX1A; APP; PSEN1; LIN7A; PSEN2; LIN7C; DLG1; APBB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

APBA1 is supported by BioGPS gene expression data to be expressed in Raji

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

93kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-APBA1 (AVARP13059_P050-Biotin) antibody

Protein Length

837

NCBI Gene Symbol

APBA1

NCBI GB Accession Number

APBA1

Host or Source

Rabbit

Protein Name

Amyloid beta A4 precursor protein-binding family A member 1

Nucleotide Accession Number

NM_001163

Peptide Sequence

PPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTD

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