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HTR2A Antibody - N-terminal region : HRP (AVARP13044_P050-HRP)

Product Specifications

Gene Name

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Gene Aliases

HTR2, 5-HT2A

Gene ID

3356

Swiss Prot

P28223

Accession Number

NP_000612

Host

Rabbit

Reactivity

Human, Mouse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A

Target

HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Partner Proteins

LYN; CBL; NDUFB10; ANKS1B; MRPL28; EIF3F; DLG4; PON2; NME3; GNAQ; PPP5C; MAP1A; RPS6KA3; NTRK3; JAK2; GNA11; GNAI1; GLUL

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

HTR2A is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 78%; Pig: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Yoon, H.K. (er) Prog. Neuropsychopharmacol. Biol. Psychiatry (2008) In press

Shipping Conditions

Wet Ice

Product Datasheet

Anti-HTR2A (AVARP13044_P050-HRP) antibody

Protein Length

471

NCBI Gene Symbol

HTR2A

NCBI GB Accession Number

HTR2A

Host or Source

Rabbit

Protein Name

5-hydroxytryptamine receptor 2A

Nucleotide Accession Number

NM_000621

Peptide Sequence

DILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSEN

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