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HTR2A Antibody - N-terminal region : Biotin (AVARP13044_P050-Biotin)

Product Specifications

Gene Name

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Gene Aliases

HTR2, 5-HT2A

Gene ID

3356

Swiss Prot

P28223

Accession Number

NP_000612

Host

Rabbit

Reactivity

Human, Mouse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A

Target

HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Partner Proteins

LYN; CBL; NDUFB10; ANKS1B; MRPL28; EIF3F; DLG4; PON2; NME3; GNAQ; PPP5C; MAP1A; RPS6KA3; NTRK3; JAK2; GNA11; GNAI1; GLUL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

HTR2A is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 78%; Pig: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Yoon, H.K. (er) Prog. Neuropsychopharmacol. Biol. Psychiatry (2008) In press

Shipping Conditions

Wet Ice

Protein Length

471

NCBI Gene Symbol

HTR2A

NCBI GB Accession Number

HTR2A

Host or Source

Rabbit

Protein Name

5-hydroxytryptamine receptor 2A

Nucleotide Accession Number

NM_000621

Peptide Sequence

DILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSEN

Frequently Asked Questions

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