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GDI2 Antibody - C-terminal region : Biotin (AVARP13037_P050-Biotin)

Product Specifications

Gene Name

GDP dissociation inhibitor 2

Gene Aliases

RABGDIB, HEL-S-46e

Gene ID

2665

Swiss Prot

P50395

Accession Number

NP_001485

Host

Rabbit

Reactivity

Human, Mouse, Guinea Pig, Horse, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GDI2

Target

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.

Partner Proteins

HUWE1; UBC; SUMO2; DUT; BAG3; IQCB1; GLRA2; FN1; SMURF1; RAB1A; RAB11B; AIP; ISG15; SIRT7; ELAVL1; Rab5c; Cdk1; Mapk13; RAB24; RAB11A; RAB9A; RAB5A; RAB4A; RAB2A; RAB8A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

GDI2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Bruneel, A., et al., (2005) Proteomics 5 (15), 3876-3884

Shipping Conditions

Wet Ice

Protein Length

445

NCBI Gene Symbol

GDI2

NCBI GB Accession Number

GDI2

Host or Source

Rabbit

Protein Name

Rab GDP dissociation inhibitor beta

Nucleotide Accession Number

NM_001494

Peptide Sequence

EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHF

Frequently Asked Questions

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