GDI2 Antibody - C-terminal region : Biotin (AVARP13037_P050-Biotin)
Product Specifications
Gene Name
GDP dissociation inhibitor 2
Gene Aliases
RABGDIB, HEL-S-46e
Gene ID
2665
Swiss Prot
P50395
Accession Number
NP_001485
Host
Rabbit
Reactivity
Human, Mouse, Guinea Pig, Horse, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GDI2
Target
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.
Partner Proteins
HUWE1; UBC; SUMO2; DUT; BAG3; IQCB1; GLRA2; FN1; SMURF1; RAB1A; RAB11B; AIP; ISG15; SIRT7; ELAVL1; Rab5c; Cdk1; Mapk13; RAB24; RAB11A; RAB9A; RAB5A; RAB4A; RAB2A; RAB8A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
GDI2 is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Bruneel, A., et al., (2005) Proteomics 5 (15), 3876-3884
Shipping Conditions
Wet Ice
Protein Length
445
NCBI Gene Symbol
GDI2
NCBI GB Accession Number
GDI2
Host or Source
Rabbit
Protein Name
Rab GDP dissociation inhibitor beta
Nucleotide Accession Number
NM_001494
Peptide Sequence
EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHF
Frequently Asked Questions
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