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GABRD Antibody - N-terminal region : FITC (AVARP13032_P050-FITC)

Selected Variant

AVARP13032_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Gamma-aminobutyric acid (GABA) A receptor, delta

Gene Aliases

EJM7, EIG10, GEFSP5

Gene ID

2563

Swiss Prot

O14764

Accession Number

NP_000806

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GABRD

Target

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit.

Partner Proteins

NOTCH2NL; UBQLN1; UBQLN4; UBC

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Emberger, W., et al., (2000) Cytogenet. Cell Genet. 89 (3-4), 281-282

Shipping Conditions

Wet Ice

Protein Length

452

NCBI Gene Symbol

GABRD

NCBI GB Accession Number

GABRD

Host or Source

Rabbit

Protein Name

Gamma-aminobutyric acid receptor subunit delta

Nucleotide Accession Number

NM_000815

Peptide Sequence

MDAPARLLAPLLLLCAQQLRGTRAMNDIGDYVGSNLEISWLPNLDGLIAG

Subunit

Delta

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