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CHRND Antibody - N-terminal region : Biotin (AVARP13022_P050-Biotin)

Selected Variant

AVARP13022_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Cholinergic receptor, nicotinic, delta (muscle)

Gene Aliases

ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Gene ID

1144

Swiss Prot

Q07001

Accession Number

NP_000742

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHRND

Target

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Partner Proteins

GRB2; CHRNA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Pig: 100%; Rabbit: 86%; Rat: 85%; Zebrafish: 78%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Engel, A.G., et al., (1996) Hum. Mol. Genet. 5 (9), 1217-1227

Shipping Conditions

Wet Ice

Protein Length

517

NCBI Gene Symbol

CHRND

NCBI GB Accession Number

CHRND

Host or Source

Rabbit

Protein Name

Acetylcholine receptor subunit delta

Nucleotide Accession Number

NM_000751

Peptide Sequence

LTLGLLAALAVCGSWGLNEEERLIRHLFQEKGYNKELRPVAHKEESVDVA

Subunit

Delta

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