CHRNB2 Antibody - N-terminal region : Biotin (AVARP13020_T100-Biotin)
Product Specifications
Gene Name
Cholinergic receptor, nicotinic, beta 2 (neuronal)
Gene Aliases
EFNL3, nAChRB2
Gene ID
1141
Swiss Prot
P17787
Accession Number
NP_000739
Host
Rabbit
Reactivity
Human, Mouse, Cow, Dog, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNB2
Target
The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies.
Partner Proteins
CRELD2; CHRNA4; CHRNA2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Zebrafish: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
References & Citations
Hales, T.G., et al., (2006) J. Biol. Chem. 281 (12), 8062-8071
Shipping Conditions
Wet Ice
Protein Length
502
NCBI Gene Symbol
CHRNB2
NCBI GB Accession Number
CHRNB2
Host or Source
Rabbit
Protein Name
Neuronal acetylcholine receptor subunit beta-2
Nucleotide Accession Number
NM_000748
Peptide Sequence
SGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISV
Subunit
Beta-2
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