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CHRNB2 Antibody - N-terminal region : Biotin (AVARP13020_T100-Biotin)

Product Specifications

Gene Name

Cholinergic receptor, nicotinic, beta 2 (neuronal)

Gene Aliases

EFNL3, nAChRB2

Gene ID

1141

Swiss Prot

P17787

Accession Number

NP_000739

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNB2

Target

The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies.

Partner Proteins

CRELD2; CHRNA4; CHRNA2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Hales, T.G., et al., (2006) J. Biol. Chem. 281 (12), 8062-8071

Shipping Conditions

Wet Ice

Protein Length

502

NCBI Gene Symbol

CHRNB2

NCBI GB Accession Number

CHRNB2

Host or Source

Rabbit

Protein Name

Neuronal acetylcholine receptor subunit beta-2

Nucleotide Accession Number

NM_000748

Peptide Sequence

SGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISV

Subunit

Beta-2

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