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HTR4 Antibody - middle region : HRP (AVARP13017_P050-HRP)

Product Specifications

Gene Name

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Gene Aliases

5-HT4, 5-HT4R

Gene ID

3360

Swiss Prot

Q13639

Accession Number

NP_000861

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HTR4

Target

HTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine) . The protein is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine) . The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.

Partner Proteins

UBC; HTR4; ADRB2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 88%; Dog: 100%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 100%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Ji, X., (2008) Neurosci. Lett. 435 (2), 95-98

Shipping Conditions

Wet Ice

Product Datasheet

Anti-HTR4 (AVARP13017_P050-HRP) antibody

Protein Length

388

NCBI Gene Symbol

HTR4

NCBI GB Accession Number

HTR4

Host or Source

Rabbit

Protein Name

5-hydroxytryptamine receptor 4

Nucleotide Accession Number

NM_000870

Peptide Sequence

GCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA

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