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AIFM2 Antibody - middle region : HRP (AVARP09054_P050-HRP)

Selected Variant

AVARP09054_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Apoptosis-inducing factor, mitochondrion-associated, 2

Gene Aliases

AMID, FSP1, PRG3

Gene ID

84883

Swiss Prot

Q9BRQ8

Accession Number

NP_116186

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AIFM2

Target

AIFM2 has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells. The protein encoded by this gene has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells.

Partner Proteins

TP53; UBC; MYC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Human: 100%; Mouse: 80%; Rabbit: 93%; Rat: 80%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Gong, M., (2007) J. Biol. Chem. 282 (41), 30331-30340

Shipping Conditions

Wet Ice

Protein Length

373

NCBI Gene Symbol

AIFM2

NCBI GB Accession Number

AIFM2

Host or Source

Rabbit

Protein Name

Apoptosis-inducing factor 2

Nucleotide Accession Number

NM_032797

Peptide Sequence

GALTFLLSMGRNDGVGQISGFYVGRLMVRLTKSRDLFVSTSWKTMRQSPP

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