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TFDP1 Antibody - middle region : FITC (AVARP09052_P050-FITC)

Product Specifications

Gene Name

Transcription factor Dp-1

Gene Aliases

DP1, DILC, Dp-1, DRTF1

Gene ID

7027

Swiss Prot

Q14186

Accession Number

NP_009042

Host

Rabbit

Reactivity

Human, Mouse, Cow, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TFDP1

Target

The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells. The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors; see TFDP2 (MIM 602160) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; E2F6; E2F4; SIAH1; E2F3; E2F2; E2F1; CDK6; PRPF31; CDK2; CDK1; SOCS3; RB1; PCGF6; RYBP; YAF2; RNF2; ELAVL1; LIN9; LIN54; LIN37; RBL2; SERTAD2; NPDC1; E2F5; TP53; RBL1; CDK3; TP53BP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Human: 100%; Mouse: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Datta, A., (2005) Mol. Cell. Biol. 25 (18), 8024-8036

Shipping Conditions

Wet Ice

Product Datasheet

Anti-TFDP1 (AVARP09052_P050-FITC) antibody

Protein Length

410

NCBI Gene Symbol

TFDP1

NCBI GB Accession Number

TFDP1

Host or Source

Rabbit

Protein Name

Transcription factor Dp-1

Nucleotide Accession Number

NM_007111

Peptide Sequence

SASDLTNGADGMLATSSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDED

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