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PDCD4 Antibody - N-terminal region : FITC (AVARP09045_P050-FITC)

Selected Variant

AVARP09045_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Programmed cell death 4 (neoplastic transformation inhibitor)

Gene Aliases

H731

Gene ID

27250

Swiss Prot

Q53EL6

Accession Number

NP_663314

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PDCD4

Target

PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of its gene is modulated by cytokines in natural killer and T cells. PDCD4 is thought to play a role in apoptosis but the specific role has not yet been determined.This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.

Partner Proteins

EIF4A2; FBXW11; EIF4A3; PAIP1; ARPC1B; UFD1L; TPD52; BTF3; AAMP; IGSF8; CD81; DAXX; UBC; CSNK2A1; VCP; NR1H2; PSEN2; PSEN1; NAP1L1; APOE; BTRC; RPS6KA1; EIF4A1; ELAVL1; SUMO2; EMD; PDCD4; EIF4G1; RPL5; RPLP1; RPS13

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Yang, H.S., et al., (2004) Mol. Cell. Biol. 24 (9), 3894-3906

Shipping Conditions

Wet Ice

Protein Length

458

NCBI Gene Symbol

PDCD4

NCBI GB Accession Number

PDCD4

Host or Source

Rabbit

Protein Name

Programmed cell death protein 4

Nucleotide Accession Number

NM_145341

Peptide Sequence

MTKYPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKR

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