RNASEL Antibody - C-terminal region : FITC (AVARP09034_T100-FITC)
Selected Variant
AVARP09034_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Gene Aliases
RNS4, PRCA1
Gene ID
6041
Swiss Prot
Q05823
Accession Number
NP_066956
Host
Rabbit
Reactivity
Human, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human RNASEL
Target
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
Partner Proteins
TCF12; UBC; ABCE1; AR; GSPT1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 78%; Dog: 92%; Horse: 100%; Human: 100%; Pig: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
84kDa
References & Citations
Nakazato, H., et al., (2003) Br. J. Cancer 89 (4), 691-696.
Shipping Conditions
Wet Ice
Protein Length
741
NCBI Gene Symbol
RNASEL
NCBI GB Accession Number
RNASEL
Host or Source
Rabbit
Protein Name
2-5A-dependent ribonuclease
Nucleotide Accession Number
NM_021133
Peptide Sequence
MKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCDGA
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