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HSPD1 Antibody - C-terminal region : Biotin (AVARP09014_P050-Biotin)

Selected Variant

AVARP09014_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Heat shock 60kDa protein 1 (chaperonin)

Gene Aliases

HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60

Gene ID

3329

Swiss Prot

P10809

Accession Number

NP_002147

Host

Rabbit

Reactivity

Human, Rat, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1

Target

HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Partner Proteins

RGS20; NOTCH2NL; KRTAP10-3; KRTAP10-8; SAMD3; KRT40; LZTS2; CEP70; HUWE1; TMCC2; KRT31; KRTAP5-9; FUS; TUBGCP3; AURKB; VCP; UBC; TUBG1; AURKA; SUMO3; LGALS3BP; CDC20; STAU1; LGR4; NEDD8; MDM2; ERG; ASB4; EED; MAPK14; ATP6V1A; RAB1B; C12orf10; NAGK; C11orf

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Guinea Pig: 90%; Human: 84%; Rabbit: 84%; Rat: 84%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Hewamadduma, C.A., (2008) Neurology 70 (19), 1717-1718

Shipping Conditions

Wet Ice

Protein Length

573

NCBI Gene Symbol

HSPD1

NCBI GB Accession Number

HSPD1

Host or Source

Rabbit

Protein Name

60 kDa heat shock protein, mitochondrial

Nucleotide Accession Number

NM_002156

Peptide Sequence

PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGG

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