HSPD1 Antibody - C-terminal region : Biotin (AVARP09014_P050-Biotin)
Selected Variant
AVARP09014_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Heat shock 60kDa protein 1 (chaperonin)
Gene Aliases
HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60
Gene ID
3329
Swiss Prot
P10809
Accession Number
NP_002147
Host
Rabbit
Reactivity
Human, Rat, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1
Target
HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Partner Proteins
RGS20; NOTCH2NL; KRTAP10-3; KRTAP10-8; SAMD3; KRT40; LZTS2; CEP70; HUWE1; TMCC2; KRT31; KRTAP5-9; FUS; TUBGCP3; AURKB; VCP; UBC; TUBG1; AURKA; SUMO3; LGALS3BP; CDC20; STAU1; LGR4; NEDD8; MDM2; ERG; ASB4; EED; MAPK14; ATP6V1A; RAB1B; C12orf10; NAGK; C11orf
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Guinea Pig: 90%; Human: 84%; Rabbit: 84%; Rat: 84%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
References & Citations
Hewamadduma, C.A., (2008) Neurology 70 (19), 1717-1718
Shipping Conditions
Wet Ice
Protein Length
573
NCBI Gene Symbol
HSPD1
NCBI GB Accession Number
HSPD1
Host or Source
Rabbit
Protein Name
60 kDa heat shock protein, mitochondrial
Nucleotide Accession Number
NM_002156
Peptide Sequence
PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGG
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