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RGS10 Antibody - middle region : FITC (AVARP09013_P050-FITC)

Selected Variant

AVARP09013_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Regulator of G-protein signaling 10

Gene ID

6001

Swiss Prot

Q96GN0

Accession Number

NP_001005339

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RGS10

Target

RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G (I) -ALPHA and G (Z) - alpha but fails to interact with the structurally and functionally distinct G (S) -alpha subunit. Activity on G (Z) -alpha is inhibited by palmitoylation of the G-protein.

Partner Proteins

UBC; ADRB2; APP; PRKACA; GNAI3; GNAO1; GNAI1; GNAZ; GNRHR; CALM1; ACP6; SAP18; EIF6

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

FACS, WB

Sample Type

There is BioGPS gene expression data showing that RGS10 is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 81%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 90%; Rat: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

References & Citations

Chatterjee, T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021

Shipping Conditions

Wet Ice

Protein Length

181

NCBI Gene Symbol

RGS10

NCBI GB Accession Number

RGS10

Host or Source

Rabbit

Protein Name

Regulator of G-protein signaling 10

Nucleotide Accession Number

NM_001005339

Peptide Sequence

DQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIYNT

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