RGS3 Antibody - C-terminal region: HRP (AVARP09007_P050-HRP)
Product Specifications
Gene Name
Regulator of G-protein signaling 3
Gene Aliases
C2PA, RGP3
Gene ID
5998
Swiss Prot
P49796-4
Accession Number
NP_570613
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human RGS3
Target
RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
Partner Proteins
GORASP2; UBC; PLSCR1; SUMO2; HES4; GNAI2; GNA11; APP; ACD; ARRB1; Nedd4; IRF5; ISG15; CNKSR2; PAX6; GLS2; YWHAE; HIPK3; PARK2; MAPK12; RGS3; YWHAB; YWHAZ; EFNB2; SCN5A; EFNB1; YWHAQ; GNAI3; GRIN2A; ESR1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
101kDa
Shipping Conditions
Wet Ice
Specificity
P49796
Protein Length
917
NCBI Gene Symbol
RGS3
Protein Name
Regulator of G-protein signaling 3
Nucleotide Accession Number
NM_130795
Curated Selection
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