RGS3 Antibody - C-terminal region : Biotin (AVARP09007_P050-Biotin)
Product Specifications
Gene Name
Regulator of G-protein signaling 3
Gene Aliases
C2PA, RGP3
Gene ID
5998
Swiss Prot
P49796-4
Accession Number
NP_570613
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human RGS3
Target
RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
Partner Proteins
GORASP2; UBC; PLSCR1; SUMO2; HES4; GNAI2; GNA11; APP; ACD; ARRB1; Nedd4; IRF5; ISG15; CNKSR2; PAX6; GLS2; YWHAE; HIPK3; PARK2; MAPK12; RGS3; YWHAB; YWHAZ; EFNB2; SCN5A; EFNB1; YWHAQ; GNAI3; GRIN2A; ESR1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
101kDa
References & Citations
Yau, D.M., (2008) Mol. Pharmacol. 73 (5), 1356-1361
Shipping Conditions
Wet Ice
Specificity
P49796
Protein Length
917
NCBI Gene Symbol
RGS3
NCBI GB Accession Number
RGS3
Host or Source
Rabbit
Protein Name
Regulator of G-protein signaling 3
Nucleotide Accession Number
NM_130795
Peptide Sequence
KDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog