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CCL18 Antibody - middle region : HRP (AVARP07049_P050-HRP)

Selected Variant

AVARP07049_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)

Gene Aliases

CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18

Gene ID

6362

Swiss Prot

P55774

Accession Number

NP_002979

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CCL18

Target

CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.

Partner Proteins

C14orf1; UNC119; CRMP1; TLE1; TP53; EEF1A1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

10kDa

References & Citations

Schraufstatter, I., et al., (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 286 (3), L494-L501

Shipping Conditions

Wet Ice

Protein Length

89

NCBI Gene Symbol

CCL18

NCBI GB Accession Number

CCL18

Host or Source

Rabbit

Protein Name

C-C motif chemokine 18

Nucleotide Accession Number

NM_002988

Peptide Sequence

PQKFIVDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA

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