CXCL12 Antibody - middle region : HRP (AVARP07031_P050-HRP)
Selected Variant
AVARP07031_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Chemokine (C-X-C motif) ligand 12
Gene Aliases
IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12
Gene ID
6387
Swiss Prot
P48061
Accession Number
NP_000600
Host
Rabbit
Reactivity
Rat, Cow, Dog, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CXCL12
Target
Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
Partner Proteins
DAZAP2; CXCR4; CXCL12; DPP4; CD4; FN1; ELANE; MMP2; CTSG; VCAN; PF4
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 90%; Dog: 100%; Pig: 100%; Rat: 90%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
11kDa
References & Citations
Sadir, R., et al., (2004) J. Biol. Chem. 279 (42), 43854-43860
Shipping Conditions
Wet Ice
Protein Length
93
NCBI Gene Symbol
CXCL12
NCBI GB Accession Number
CXCL12
Host or Source
Rabbit
Protein Name
Stromal cell-derived factor 1
Nucleotide Accession Number
NM_000609
Peptide Sequence
VKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
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