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CCL8 Antibody - middle region : Biotin (AVARP07026_P050-Biotin)

Selected Variant

AVARP07026_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Chemokine (C-C motif) ligand 8

Gene Aliases

HC14, MCP2, MCP-2, SCYA8, SCYA10

Gene ID

6355

Swiss Prot

P80075

Accession Number

NP_005614

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CCL8

Target

CCL8 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ACKR2; ACKR4; CCR5; CCR3; CCR2; CCR1; MMP3; VCAN; ACKR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

9kDa

References & Citations

Hori, T., (2008) Blood 111 (8), 4403-4412

Shipping Conditions

Wet Ice

Protein Length

99

NCBI Gene Symbol

CCL8

NCBI GB Accession Number

CCL8

Host or Source

Rabbit

Protein Name

C-C motif chemokine 8

Nucleotide Accession Number

NM_005623

Peptide Sequence

SYTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP

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