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CCR4 Antibody - middle region : Biotin (AVARP07017_P050-Biotin)

Product Specifications

Gene Name

Chemokine (C-C motif) receptor 4

Gene Aliases

CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, HGCN:14099

Gene ID

1233

Swiss Prot

P51679

Accession Number

NP_005499

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CCR4

Target

CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657

Partner Proteins

CCL22; CCL17; CCL5; CCL3; ADRBK2; ADRBK1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

CCR4 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 87%; Dog: 87%; Human: 100%; Mouse: 87%; Rat: 87%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Nakayama, T., (2008) Oncogene 27 (23), 3221-3232

Shipping Conditions

Wet Ice

Protein Length

360

NCBI Gene Symbol

CCR4

NCBI GB Accession Number

CCR4

Host or Source

Rabbit

Protein Name

C-C chemokine receptor type 4

Nucleotide Accession Number

NM_005508

Peptide Sequence

TERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTL

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