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CDC34 Antibody - middle region : Biotin (AVARP03048_P050-Biotin)

Selected Variant

AVARP03048_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Cell division cycle 34 homolog (S. cerevisiae)

Gene Aliases

UBC3, UBCH3, UBE2R1, E2-CDC34

Gene ID

997

Swiss Prot

P49427

Accession Number

NP_004350

Host

Rabbit

Reactivity

Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CDC34

Target

CDC34 catalyzes the covalent attachment of ubiquitin to other proteins. CDC34 may be involved in degradation of katenin.The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

FBXW11; UBC; RBX1; SIAH1; SDCBP; PPARG; ZNRF1; FBXW7; BTRC; UBA1; CDC34; HIST1H2BA; UBI4; MARCH1; MARCH2; GNPDA1; USP5; WARS; RAD23A; ANAPC11; ING4; FBXL2; Rag1; FBXO32; ITCH; NEDD4L; WWP2; TRIM28; RNF7; CUL1; CUL3; VHL; TRIM21; SKP2; CDKN1B; CCNE1; ZFAND

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

References & Citations

Gazdoiu, S., (2007) Mol. Cell. Biol. 27 (20), 7041-7052

Shipping Conditions

Wet Ice

Protein Length

236

NCBI Gene Symbol

CDC34

NCBI GB Accession Number

CDC34

Host or Source

Rabbit

Protein Name

Ubiquitin-conjugating enzyme E2 R1

Nucleotide Accession Number

NM_004359

Peptide Sequence

TLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEEADSCFGDDEDDSGTEE

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