RBX1 Antibody - middle region : FITC (AVARP03042_T100-FITC)
Selected Variant
AVARP03042_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Ring-box 1, E3 ubiquitin protein ligase
Gene Aliases
ROC1, RNF75, BA554C12.1
Gene ID
9978
Swiss Prot
P62877
Accession Number
NP_055063
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RBX1
Target
ROC1 encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.
Partner Proteins
CDT1; CDC34; KEAP1; UBE2L6; UBE2M; CUL1; CUL3; CUL4B; UBE2D3; UBE2D2; UBE2D1; DAB2IP; UBC; TP53; PRAME; DCUN1D1; CUL2; DCUN1D3; MAP4K1; VHL; NEDD4; MTSS1; VRK2; HIST1H4A; GFPT1; CTNNB1; CCNE1; DCUN1D5; FBXL5; RHOBTB3; SAMHD1; UBC12; FBXL15; UBE2R2; SERTAD
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
12kDa
References & Citations
Zheng, N., et al., (2002) Nature 416 (6882), 703-709.
Shipping Conditions
Wet Ice
Protein Length
108
NCBI Gene Symbol
RBX1
NCBI GB Accession Number
RBX1
Host or Source
Rabbit
Nucleotide Accession Number
NM_014248
Peptide Sequence
NQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
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