CDC25B Antibody - N-terminal region : Biotin (AVARP03041_P050-Biotin)
Selected Variant
AVARP03041_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Cell division cycle 25 homolog B (S. pombe)
Gene ID
994
Swiss Prot
P30305
Accession Number
NP_068659
Host
Rabbit
Reactivity
Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B
Target
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.
Partner Proteins
BTRC; UBC; FBXW11; MAPK9; CDK5; CDK1; YWHAQ; MAPKAPK2; UBD; BRSK2; CDC14A; CDK2; Cdc25b; FOXM1; BRSK1; FHL3; KAT2B; MELK; YWHAE; CHEK1; AURKA; SFN; YWHAB; YWHAZ; MAPK14; CREBBP; AR; ESR1; CSNK2B; CSNK2A1; YWHAH; PGR; PHB2; KRT85; KRT35; KRT31
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
CDC25B is supported by BioGPS gene expression data to be expressed in Daudi
Concentration
0.5 mg/ml
Homology
Dog: 76%; Guinea Pig: 100%; Horse: 90%; Pig: 92%; Rabbit: 84%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
65kDa
References & Citations
Uchida, S., et al., (2004) Biochem. Biophys. Res. Commun. 316 (1), 226-232
Shipping Conditions
Wet Ice
Protein Length
580
NCBI Gene Symbol
CDC25B
NCBI GB Accession Number
CDC25B
Host or Source
Rabbit
Protein Name
M-phase inducer phosphatase 2
Nucleotide Accession Number
NM_021873
Peptide Sequence
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASS
Price
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