CDK5 Antibody - N-terminal region : Biotin (AVARP03025_P050-Biotin)

Product Specifications

Gene Name

Cyclin-dependent kinase 5

Gene Aliases

LIS7, PSSALRE

Gene ID

1020

Swiss Prot

Q00535

Accession Number

NP_004926

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CDK5

Target

CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase.

Partner Proteins

CHFR; CCND2; CDKN1A; EGFR; UBC; DCLK3; CDK5; CCNE1; CDK5R1; CABLES1; CABLES2; STIP1; CDKN1B; CCND3; CCNB1; C2CD5; KIAA0195; FIBP; PPARG; CDK18; HSP90AB1; HSP90AA1; HIST1H1B; GLUD1; CDK3; CDC25B; CCT6A; CCNA2; CCT3; TCP1; CCT5; CDC37; CCT8; CCT2; CCT4; CCT

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Sample Type

CDK5 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.