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CDK7 Antibody - C-terminal region : HRP (AVARP03009_P050-HRP)

Product Specifications

Gene Name

Cyclin-dependent kinase 7

Gene Aliases

CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15

Gene ID

1022

Swiss Prot

P50613

Accession Number

NP_001790

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CDK7

Target

Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti

Partner Proteins

UBC; RPA3; RPA2; RPA1; GTF2H4; GTF2H3; GTF2H2; GTF2H1; ERCC5; ERCC3; ERCC2; CDK7; CCNH; ATP2B4; A2M; GTF2H5; SRPK2; SRPK1; MNAT1; TP53; CDK2; CTD; MBP; CDK1; CCNB1; CCNA2; Dlg4; UVSSA; HSP90AA1; HSD17B4; HLA-DQA1; SUPT5H; POLR2A; GTF2E2; GTF2E1; CDK9; APP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 94%; Guinea Pig: 94%; Horse: 100%; Human: 100%; Mouse: 88%; Pig: 100%; Rat: 88%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Tassan, J.P., et al., (1994) J. Cell Biol. 127:467-478.

Shipping Conditions

Wet Ice

Product Datasheet

Anti-CDK7 (AVARP03009_P050-HRP) antibody

Protein Length

346

NCBI Gene Symbol

CDK7

NCBI GB Accession Number

CDK7

Host or Source

Rabbit

Protein Name

Cyclin-dependent kinase 7

Nucleotide Accession Number

NM_001799

Peptide Sequence

NRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF

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