YWHAQ Antibody - N-terminal region: Biotin (AVARP02062_P050-Biotin)
Product Specifications
Gene Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene Aliases
1C5, HS1, 14-3-3
Gene ID
10971
Swiss Prot
P27348
Accession Number
NP_006817
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ
Target
YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Partner Proteins
UBC; TNFAIP3; TRIM42; RAF1; PIK3R2; PIK3C3; FUS; DTL; MAPT; ABL1; SGK1; SIK3; SUMO2; TUBGCP3; IRS4; HDAC5; HDAC4; STAU1; MDM2; TGM2; SMS; ALDH7A1; YWHAZ; YWHAH; GNAI3; G6PD; EIF5; EEF2; ECHS1; CAPNS1; CAPN1; LDHB; YWHAG; YWHAB; VCL; UBE2V1; TXNDC5; SMEK2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
YWHAQ is strongly supported by BioGPS gene expression data to be expressed in SW620
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
Shipping Conditions
Wet Ice
Protein Length
245
NCBI Gene Symbol
YWHAQ
Protein Name
14-3-3 protein theta
Nucleotide Accession Number
NM_006826
Curated Selection
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