YWHAQ Antibody - N-terminal region : Biotin (AVARP02062_P050-Biotin)

YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

UBC; TNFAIP3; TRIM42; RAF1; PIK3R2; PIK3C3; FUS; DTL; MAPT; ABL1; SGK1; SIK3; SUMO2; TUBGCP3; IRS4; HDAC5; HDAC4; STAU1; MDM2; TGM2; SMS; ALDH7A1; YWHAZ; YWHAH; GNAI3; G6PD; EIF5; EEF2; ECHS1; CAPNS1; CAPN1; LDHB; YWHAG; YWHAB; VCL; UBE2V1; TXNDC5; SMEK2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.