TP53 Antibody - C-terminal region : Biotin (AVARP02055_T100-Biotin)
Selected Variant
AVARP02055_T100-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
P53, BCC7, LFS1, BMFS5, TRP53
Gene ID
7157
Swiss Prot
P04637
Accession Number
NP_000537
Host
Rabbit
Reactivity
Human, Rat, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TP53
Target
TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
TP53 is strongly supported by BioGPS gene expression data to be expressed in DU145
Concentration
0.5 mg/ml
Homology
Horse: 93%; Human: 100%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
44kDa
References & Citations
Zakut-Houri, R., et al., (1985) EMBO J. 4: 1251-1255.
Shipping Conditions
Wet Ice
Protein Length
393
NCBI Gene Symbol
TP53
NCBI GB Accession Number
TP53
Host or Source
Rabbit
Protein Name
Cellular tumor antigen p53
Nucleotide Accession Number
NM_000546
Peptide Sequence
RELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPD
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