TNFRSF18 Antibody - C-terminal region : FITC (AVARP02052_P050-FITC)
Selected Variant
AVARP02052_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Tumor necrosis factor receptor superfamily, member 18
Gene Aliases
AITR, GITR, CD357, GITR-D, ENERGEN
Gene ID
8784
Swiss Prot
Q9Y5U5
Accession Number
NP_004186
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
Target
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Partner Proteins
LNX1; TRAF3; TRAF2; TRAF1; TNFSF18; TNFRSF18
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
26kDa
References & Citations
Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270
Shipping Conditions
Wet Ice
Protein Length
241
NCBI Gene Symbol
TNFRSF18
NCBI GB Accession Number
TNFRSF18
Host or Source
Rabbit
Protein Name
Tumor necrosis factor receptor superfamily member 18
Nucleotide Accession Number
NM_004195
Peptide Sequence
LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
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