BCL2L1 Antibody - N-terminal region : FITC (AVARP02008_P050-FITC)
Selected Variant
AVARP02008_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
BCL2-like 1
Gene Aliases
BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S
Gene ID
598
Swiss Prot
Q07817
Accession Number
NP_612815
Host
Rabbit
Reactivity
Human, Cow, Dog, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1
Target
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
Partner Proteins
BCL2L1; BCL2; BAX; BAD; BMF; BBC3; CASP8AP2; BECN1; UBC; TPT1; TP53BP2; ced-9; ced-4; PGAM5; CDKN2A; CASP1; BCL2L11; HRK; PMAIP1; BIK; BID; PARK2; PINK1; BAK1; RAD9A; AKT1; Mapk1; ATXN3; CLU; BCAP31; CRYAB; CRYAA; BFAR; PPP1CC; PPP1CA; ACTB; UBR1; METTL23
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 100%; Human: 100%; Pig: 92%; Rabbit: 84%; Sheep: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
26kDa
References & Citations
Bachelor, M.A. et al., (2004) J. Biol. Chem. 279 (41), 42658-42668
Shipping Conditions
Wet Ice
Protein Length
233
NCBI Gene Symbol
BCL2L1
NCBI GB Accession Number
BCL2L1
Host or Source
Rabbit
Protein Name
Bcl-2-like protein 1
Nucleotide Accession Number
NM_138578
Peptide Sequence
LVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSW
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