H3F3A (Phospho-Histone H3) Antibody - N-terminal region : HRP (AVARP01011_P050-HRP)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

RAD6; SETD7; WHSC1L1; PRDM2; WHSC1; KMT2A; PHF7; CBX5; TRIM28; ING2; UBC; K07C5.3; APLF; UHRF1; NEDD8; CUL4A; EZH2; ASF1B; ASF1A; MMS22L; IGSF8; TONSL; ICAM1; CD81; AURKA; MLLT1; TAF8; TAF3; TAF9B; PHF21A; ING4; PRAME; KAT6B; CBX6; PHF8; PHF2; ITGA4; TAF1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.