BCL2 Antibody - N-terminal region : Biotin (AVARP01005_P050-Biotin)
Selected Variant
AVARP01005_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
B-cell CLL/lymphoma 2
Gene Aliases
Bcl-2, PPP1R50
Gene ID
596
Swiss Prot
P10415
Accession Number
NP_000624
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2
Target
The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Partner Proteins
KEAP1; SQSTM1; BECN1; UBC; TP53BP2; BID; BCL2L1; BCL2; BAX; BAD; ATP2A3; NR4A1; KRAS; PPID; MDM4; BNIP3; BFAR; CDK1; BAG3; RAF1; IKBKG; TP53; PPP3CC; FKBP8; MAPK8; IKBKB; HSP90AA1; HIF1A; CRYAB; CHUK; PML; BRCA1; AMBRA1; ATG12; BIK; CISD2; MEX3D; PPP1CC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
26kDa
References & Citations
Chen, R., et al., (2004) J. Cell Biol. 166 (2), 193-203
Shipping Conditions
Wet Ice
Protein Length
239
NCBI Gene Symbol
BCL2
NCBI GB Accession Number
BCL2
Host or Source
Rabbit
Protein Name
Apoptosis regulator Bcl-2
Nucleotide Accession Number
NM_000633
Peptide Sequence
GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD
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