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TRAP1 Antibody - N-terminal region : HRP (AVARP00012_T100-HRP)

Selected Variant

AVARP00012_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

TNF receptor-associated protein 1

Gene Aliases

HSP75, HSP 75, HSP90L, TRAP-1

Gene ID

10131

Swiss Prot

Q12931

Accession Number

NP_057376

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRAP1

Target

Suppression of the expression of TRAP1 in mitochondria might play an important role in the induction of apoptosis caused via formation of ROS.

Partner Proteins

SUMO2; SUMO3; LGALS3BP; CEP72; CEP250; UBC; MDM2; OGFR; MAGED2; FKBP5; USP7; EIF2AK4; RPS19; RPL7A; HSPA5; GAPDH; EIF4A1; EEF1G; EEF1A1; FBXO6; PRKACB; CDK9; CDK5; CDK4; ESX1; TPM3; FN1; C1QBP; TRAF3IP1; WDHD1; VDAC2; VAMP2; APP; CUL3; CUL5; PSMC4; RAD21

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

TRAP1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 85%; Guinea Pig: 92%; Human: 100%; Mouse: 85%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

80kDa

References & Citations

Masuda, Y., et al., (2004) J. Biol. Chem. 279 (41), 42503-42515 -2004 (41), 42503-42515

Shipping Conditions

Wet Ice

Protein Length

704

NCBI Gene Symbol

TRAP1

NCBI GB Accession Number

TRAP1

Host or Source

Rabbit

Protein Name

Heat shock protein 75 kDa, mitochondrial

Nucleotide Accession Number

NM_016292

Peptide Sequence

AQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEF

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